Role of SNPs of CPTIA and CROT genes in the carnitine-shuttle in coronary artery disease: a case control study

Yazar
Bugra, Zehra
Ozturk, Oguz
Aydogan, Hülya
Demircan, Aslihan
Coskunpinar, Ender
Kanca, Deniz
Ozkara, Gulcin
Yanar, Fatih
Kurnaz-Gomleksiz, Ozlem
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Özet
Objective: Fatty acid beta-oxidation defects can lead to difficulties at covering energy requirement of heart. The carnitine-shuttle is responsible for the transfering of long-chain fatty acids from the internal mitochondrial membrane. The role of genetic variants of the enzymes in the carnitine shuttle in coronary artery disease (CAD) has not been studied. Therefore, we performed a case-control study investigating the possible relation between the CPTIA-rs3019613 and CROT-rs2214930 gene variations located carnitine shuttle and CAD risk.
Bağlantı
http://hdl.handle.net/20.500.12627/70628
https://doi.org/10.1515/tjb-2018-0546
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