The prophylactic effects of superoxide dismutase, catalase, desferrioxamine, verapamil and disulfiram in experimental colitis
Tarih
1997Yazar
Kose, H
Cokneseli, B
Koksoy, FN
Yalcin, O
Soybir, GR
Üst veri
Tüm öğe kaydını gösterÖzet
In our study we have tried to compare the prophylactic effects of superoxide dismutase (SOD), SOD+catalase (CAT), desferrioxamine, verapamil and disulfiram, which are all free oxygen radical (FOR) scavengers, in an animal model of experimental acetic acid colitis. The control group had 58.3% colonic ulcers. The SOD group (48.6% ulcerated area) and the SOD+CAT group (47.2% ulcerated area) did not show a significant difference when compared with the control group. The values were significantly different in all other groups when compared with the control group (desferrioxamine (29.2% ulcerated area): P < 0.01;verapamil (10.4% ulcerated area) and disulfiram (7.6% ulcerated area): P < 0.001.
Koleksiyonlar
- Makale [92796]