Pregnancy-associated plasma protein A (PAPP-A) and severity of coronary atherosclerosis assessed by angiographic Gensini score

Abstract

Background: Pregnancy-associated plasma protein A (PAPP-A) is a potentially proatherosclerotic metalloproteinase, which has been shown to be abundantly expressed in ruptured unstable plaques. However, changes of the PAPP-A blood levels in patients with coronary artery disease (CAD) according to the Gensini score is unknown in Turkish population.