Therapeutic vaccination in chronic hepatitis B

Tarih
2002
Yazar
Tabak, F
Senturk, H
Akdogan, M
Erdem, L
Mert, A
Sander, E
Ozbay, G
Badur, S
Ozaras, R
Üst veri
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Özet
Aims: The aim was to test the efficacy of a pre-S2-containing vaccine (Genhevac-B) in chronic hepatitis B (CHB). Twenty-five naive patients (22 male, three female; median age 35; range: 6-69 years) with CHB were recruited. The inclusion criteria were: hepatitis B e antigen (HBeAg) positive or HBV-DNA detectable with liquid hybridization; alanine aminotransferase (ALT) is at least 1.5-fold the upper normal limit and histological evidence of chronic hepatitis.
Bağlantı
http://hdl.handle.net/20.500.12627/47278
https://doi.org/10.1046/j.1440-1746.2002.02652.x
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