Efficacy of tenofovir in adefovir-experienced patients compared with treatment-naive patients with chronic hepatitis B

Date
2014
Author
Yurdaydin, Cihan
BOZDAYI, ABDURRAHMAN MİTHAT
Onel, Derya
İDİLMAN, RAMAZAN
Baran, Bulent
KESKİN, ONUR
Kabacam, Gokhan
Tuzun, Ali
Karatayli, Ersin
Karatayli, Senem
Akyuz, Filiz
Kaymakoglu, Sabahattin
Badur, Selim
Ormeci, Asli C.
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Abstract
Background: Tenofovir (TDF) has similar antiviral efficacy in both treatment-naive and lamivudine-resistant chronic hepatitis B (CHB) patients. Data on TDF use in patients with adefovir (ADV) resistance is inconsistent. The aim of our study was to assess antiviral efficacy of TDF against nucleoside analogue-naive (NN) and ADV-resistant (ADV-R) CHB and suboptimal responders to ADV (ADV-S).
URI
http://hdl.handle.net/20.500.12627/39719
https://doi.org/10.3851/imp2732
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