SERUM HS-CRP LEVELS DO NOT INDICATE THE SEVERITY OF LIVER DAMAGE IN NON-ALCOHOLIC STEATOHEPATITIS PATIENTS WITH TYPE-2 DIABETES MELLITUS

Abstract

Objective: Non-alcoholic steatohepatitis (NASH) is a commonly encountered community health problem which is associated with obesity, insulin resistance and type 2 diabetes. There is no clinical or biochemical indicator predicting the prognosis of NASH. Therefore, it is not possible to predict the course of NASH in which patients may stay as a benign condition or in which it may progress to fibrosis or rarely cirrhosis. High sensitive C-reactive protein (hs-CRP) is a commonly used acute phase reactant which increases in even mild inflammatory states. In this study, we investigated the relationship between hs-CRP and inflammation in liver tissue in cases with NASH and type 2 diabetes mellitus.