Unilateral tibial agenesia with preaxial polysyndactyly and renal disorder in two patients: a new syndrome?

Abstract

Left tibial agenesis, polysyndactyly with talipes equinovarus deformity and Grade IV vesicoureteral reflux of the right kidney are described in a 40-day-old male and an unrelated 1-month-old male, is also reported with right tibial agenesis, polysyndactyly with talipes equinovarus deformity and right kidney agenesis and left Grade V vesicoureteral reflux. No other pathology was recorded. Follow up at 1 year and 3 years, respectively, revealed normal motor and mental development. As this combination has been unpublished before, we believe that this a new syndrome. Clin Dysmorphol 10: 37-40 (C) 2001 Lippincott Williams & Wilkins.