Constituents of Cynara syriaca leaves

Abstract

Six flavonoids (apigenin, chrysoeriol, luteolin, apigenin 7-O-glucoside, chrysoeriol 7-O-glucoside, luteolin 7-O-glucoside), four phenolic acids (caffeic acid, chlorogenic acid, 1,5-dicaffeoylquinic acid, cynarin), and three sesquiterpene lactones (11,13-dihydroxy-8-desoxygrosheimin, 11,13-dihydrodeacylcynaropicrin, solstitialin) were isolated from the leaves of Cynara syriaca Boiss (Asteraceae). Three of these compounds, chrysoeriol, chrysoeriol 7-O-glucoside, and 11,13-dihydrodeacylcynaropicrin, were isolated for the first time from Cynara species. 11,13-Dihydroxy-8-desoxygrosheimin was isolated for the second time from a plant.