Lowering Uric Acid With Allopurinol Improves Insulin Resistance and Systemic Inflammation in Asymptomatic Hyperuricemia

Tarih
2015
Yazar
Takir, Mumtaz
Semerci, Aysun
ODABAŞ, ALİ RIZA
Afsar, Baris
Smits, Gerard
ALanaspa, Miguel
Sharma, Shailendra
Johnson, Richard J.
Kanbay, Mehmet
Ozkok, Abdullah
Kostek, Osman
ELÇİOĞLU, Ömer Celal
Bakan, Ali
Erek, Aybala
MUTLU, HASAN HÜSEYİN
Telci, Ozge
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Özet
Background Hyperuricemia is an independent predictor of impaired fasting glucose and type 2 diabetes, but whether it has a causal role in insulin resistance remains controversial. Here we tested the hypothesis that lowering uric acid in hyperuricemic nondiabetic subjects might improve insulin resistance.
Bağlantı
http://hdl.handle.net/20.500.12627/181026
https://doi.org/10.1097/jim.0000000000000242
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