Examining facial emotion recognition as an intermediate phenotype for psychosis: Findings from the EUGEI study

Author
Rutten, Bart P. F.
Maric, Nadja P.
Atbasoglu, Cem
Ucok, Alp
ALPTEKİN, KÖKSAL
SAKA, MERAM CAN
Aguglia, Eugenio
Arango, Celso
O'Donovan, Michael
Guloksuz, Sinan
Fusar-Poli, Laura
Pries, Lotta-Katrin
van Os, Jim
Erzin, Gamze
Delespaul, Philippe
Kenis, Gunter
Luykx, Juryen J.
Lin, Bochao D.
Richards, Alexander L.
Akdede, Berna
Binbay, Tolga
ALTINYAZAR, VESİLE
Yalincetin, Berna
GÜMÜŞ AKAY, GÜVEM
Cihan, Burgin
Soygur, Haldun
Ulas, Halis
Cankurtaran, Eylem Sahin
Kaymak, Semra Ulusoy
Mihaljevic, Marina M.
Andric-Petrovic, Sanja
Mirjanic, Tijana
Bernardo, Miguel
Mezquida, Gisela
Amoretti, Silvia
Bobes, Julio
Saiz, Pilar A.
Garcia-Portilla, Maria Paz
Sanjuan, Julio
Aguilar, Eduardo J.
Santos, Jose Luis
Jimenez-Lopez, Estela
Arrojo, Manuel
Carracedo, Angel
Lopez, Gonzalo
Gonzalez-Penas, Javier
Parellada, Mara
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Abstract
Background: Social cognition impairments, such as facial emotion recognition (FER), have been acknowledged since the earliest description of schizophrenia. Here, we tested FER as an intermediate phenotype for psychosis using two approaches that are indicators of genetic risk for schizophrenia: the proxy-genetic risk approach (family design) and the polygenic risk score for schizophrenia (PRS-SCZ).
URI
http://hdl.handle.net/20.500.12627/178498
https://doi.org/10.1016/j.pnpbp.2021.110440
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