Trends of primary glomerular disease in Turkey: TSN-GOLD registry report
Yazar
Selcuk, Nedim Yilmaz
Ulu, Sena
Altinoren, Orcun
KUTLAY, SİM
Mese, Meral
ŞAHİN, İDRİS
ÜSTÜNDAĞ, SEDAT
TÜRKMEN, KULTİGİN
YILMAZ, MEHMET EMİN
Kazancioglu, Rumeyza Turan
UZUN, ÖZCAN
CANDAN, FERHAN
Aydin, Zeki
Oygar, Deren
Aktas, Nimet
ERDEM, YUNUS
Paydas, Saime
Taymez, Dilek
Can, Basak
Kiykim, Ahmet
Koc, Leyla
Sezer, Siren
Duranay, Murat
Bardak, Simge
Altintepe, Lutfullah
Kaya, Burcu
Azak, Alper
Ecder, Sebahat Alisir
ÇAVDAR, CANER
Gul, Cuma Bulent
Kucuk, Mehmet
Ozturk, Savas
Demir, Erol
EREN, NECMİ
Sumnu, Abdullah
SEYAHİ, NURHAN
Gullulu, Mustafa
Dede, Fatih
DERİCİ, ÜLVER
Koc, Yener
ŞAHİN, GARİP
OYMAK, OKTAY
Sahin, Gulizar Manga
Tatar, Erhan
DURSUN, BELDA
Dheir, Hamad
Apaydin, Suheyla
SÜLEYMANLAR, GÜLTEKİN
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Background Although several renal biopsy registry reports have been published worldwide, there are no data on primary glomerular disease trends in Turkey. Methods Three thousand eight-hundred fifty-eight native kidney biopsy records were assessed in the Turkish Society of Nephrology Primary Glomerulopathy Working Group (TSN-GOLD) Registry. Secondary disease and transplant biopsies were not recorded in the registry. These records were divided into four periods, before 2009, 2009 to 2013, 2013-2017, and 2017-current. Results A total of 3858 patients (43.6% female, 6.8% elderly) were examined. Nephrotic syndrome was the most common biopsy indication in all periods (58.6%, 53%, 44.1%, 51.6%, respectively). In the whole cohort, IgA nephropathy (IgAN) (25.7%) was the most common PGN with male predominance (62.7%), and IgAN frequency steadily increased through the periods (x 2 = 198, p 65 years), and there was no trend in this age group. An increasing trend was seen in the frequency of overweight patients (x 2 = 37, p < 0.0001). Although the biopsy rate performed with interventional radiology gradually increased, the mean glomeruli count in the samples did not change over the periods. Conclusions In Turkey, IgAN is the most common primary glomerulonephritis, and the frequency of this is increasing.
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