The Comparison of the Clinical and Metabolic Results of Laparoscopic Roux-en-Y Gastric Bypass Versus One-Anastomosis Gastric Bypass in Morbid Obese Patients

Abstract

Background: The most effective treatment for permanent weight loss is bariatric surgery. The present study aimed to evaluate the early period effects of laparoscopic Roux-en-Y gastric bypass (LRYGB) and laparoscopic one-anastomosis gastric bypass (LOAGB) surgeries on the clinical and metabolic results. Materials and Methods: A total of 80 patients underwent bariatric surgery. The patients in Group I (n = 42) underwent LRYGB, and patients in Group II (n = 38) underwent LOAGB. Results: Clinical and laboratory improvements were detected in all diabetic patients in both groups starting from the third month after surgery. Third month and sixth month after surgery, more rapid diabetes regulation was detected in Group II (p = 0.0019 and p = 0.0016). There was an improvement in arterial blood pressure, total cholesterol, triglyceride, and low density lipoprotein in both groups. The decrease in body mass index was statistically higher in third- and sixth-month controls in Group II (p = 0.004, and p = 0.003). The ratios of excess weight loss % (EWL%) in the third- and sixth-month controls were higher in Group II, which was statistically significant (p = 0.007, and p = 0.008). Conclusions: One-anastomosis gastric bypass is associated with more rapid EWL% and type 2 diabetes remission; also, not inferior to RYGB in terms of other metabolic parameters.