Prognostic evidence of LEF1 isoforms in childhood acute lymphoblastic leukemia

Hatirnaz Ng, Ozden; Erbilgin, Yücel; Karaman, Serap; Karakas, Zeynep; Ozbek, Ugur; Toluk, Ozlem; Khodzhaev, Khusan; Tansel, Turkan; Dogru, Omer; Yildirmak, Yildiz; Nihal Ozdemir, Gul; Aylan Gelen, Sema; Zengin, Emine; Celkan, Tulin Tiraje; Kucukcankurt, Fulya; Firtina, Sinem; Can, Ismail; Sayitoglu, Müge

Yazar

Hatirnaz Ng, Ozden

Erbilgin, Yücel

Karaman, Serap

Karakas, Zeynep

Ozbek, Ugur

Toluk, Ozlem

Khodzhaev, Khusan

Tansel, Turkan

Dogru, Omer

Yildirmak, Yildiz

Nihal Ozdemir, Gul

Aylan Gelen, Sema

Zengin, Emine

Celkan, Tulin Tiraje

Kucukcankurt, Fulya

Firtina, Sinem

Can, Ismail

Sayitoglu, Müge

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Özet

Introduction The lymphoid enhancer factor 1 (LEF1) is a DNA-binding transcription factor that functions in the Wnt signaling pathway. Increased LEF1 activity is associated with progression of several types of cancer including leukemia. Here, we investigated LEF1 isoform expression and genomic variations in acute lymphoblastic leukemia (ALL).

Bağlantı

http://hdl.handle.net/20.500.12627/172297
https://avesis.istanbul.edu.tr/api/publication/8ac8a02a-d0c7-4d83-abc1-42bcdc7d4b63/file
https://doi.org/10.1111/ijlh.13513

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