Active vitamin D is cardioprotective in experimental uraemia but not in children with CKD Stages 3-5

Tarih
2021
Yazar
Fischer, Dagmar-Christiane
Soylemezoglu, Oguz
Melk, Anette
Stangl, Gabriele
Behnisch, Rouven
Shroff, Rukshana
Bacchetta, Justine
Querfeld, Uwe
Schaefer, Franz
Haffner, Dieter
Schoen, Anne
Leifheit-Nestler, Maren
Deppe, Jennifer
KARABAY BAYAZIT, AYSUN
Obrycki, Lukasz
CANPOLAT, Nur
KAPLAN BULUT, İPEK
Azukaitis, Karolis
Yilmaz, Alev
Mir, Sevgi
Yalcinkaya, Fatos
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Özet
Background. Uraemic cardiac remodelling is associated with vitamin D and Klotho deficiency, elevated fibroblast growth factor 23 (FGF23) and activation of the renin-angiotensin system (RAS). The cardioprotective properties of active vitamin D analogues in this setting are unclear.
Bağlantı
http://hdl.handle.net/20.500.12627/171223
https://doi.org/10.1093/ndt/gfaa227
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