Risk Factors and Time to Clinical Symptoms of Multiple Sclerosis Among Patients With Radiologically Isolated Syndrome

Tarih
2021
Yazar
Bourre, Bertrand
Zephir, Helene
Louapre, Celine
Le Page, Emmanuelle
Durand-Dubief, Francoise
Labauge, Pierre
Bensa, Caroline
Thouvenot, Eric
Laplaud, David
de Seze, Jerome
Ciron, Jonathan
Cabre, Philippe
Casez, Olivier
Ruet, Aurelie
Mathey, Guillaume
Berger, Eric
Moreau, Thibault
Al Khedr, Abdulatif
Derache, Nathalie
Clavelou, Pierre
Guennoc, Anne-Marie
Creange, Alain
Neau, Jean-Philippe
Tourbah, Ayman
Camdessanche, Jean-Philippe
Maarouf, Adil
Callier, Celine
Vermersch, Patrick
Kantarci, Orhun
Siva, Aksel
Azevedo, Christina
Makhani, Naila
Cohen, Mikael
Pelletier, Daniel
Okuda, Darin
Vukusic, Sandra
Lebrun-Frenay, Christine
Rollot, Fabien
Mondot, Lydiane
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Özet
IMPORTANCE Younger age, oligoclonal bands, and infratentorial and spinal cord lesions are factors associated with an increased 10-year risk of clinical conversion from radiologically isolated syndrome (RIS) to multiple sclerosis (MS). Whether disease-modifying therapy is beneficial for individuals with RIS is currently unknown.
Bağlantı
http://hdl.handle.net/20.500.12627/170659
https://doi.org/10.1001/jamanetworkopen.2021.28271
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