Show simple item record

dc.contributor.authorKilic, Elif
dc.contributor.authorKAZANCIOĞLU, Rümeyza
dc.contributor.authorDogan, Elif Ece
dc.contributor.authorCebeci, Egemen
dc.contributor.authorOzturk, Savaş
dc.contributor.authorEkinci, Iskender
dc.contributor.authorErkoc, Reha
dc.contributor.authorGÜRSU, Meltem
dc.identifier.citationEkinci I., Erkoc R., GÜRSU M., Dogan E. E. , Kilic E., Cebeci E., Ozturk S., KAZANCIOĞLU R., "Effects of fasting during the month of Ramadan on renal function in patients with autosomal dominant polycystic kidney disease", CLINICAL NEPHROLOGY, cilt.89, sa.2, ss.103-112, 2018
dc.description.abstractBackground: In this study, we aimed to examine the impact of fasting during the month of Ramadan on autosomal dominant polycystic kidney disease (ADPKD) patients with normal to near-nomial glomerular filtration rate (GFR). Materials and methods: This was a prospective observational study of patients with ADPKD, the majority of whom had normal or near-normal GFR. Patients were divided into two groups: the fasting group (FG) and the nonfasting group (NFG). Assessments in the NFG were performed 1 week before and 1 month after Ramadan. while FG patients were assessed on the last day of fasting in addition to the abovementioned visits. The following parameters were checked at each visit: blood pressure (BP), weight, sodium. potassium, blood urea nitrogen (BUN), creatinine, calcium. phosphorus, glucose, lipid profile. bicarbonate, urine density. 24-hour urine volume, 24-hour urine protein, GFR, neutrophil gelatinase-associated lipocalin (NGAL), and kidney injury molecule-1 (KIM-1). Kidney function tests were carried out on the 7th day of fasting in the FG for the identification of early kidney damage. Results: Of the overall group of 54 patients. 23 were in FG (19 female) and 31 were in NFG (18 female). There were no significant differences between the two groups in terms of age, gender, ADPKD duration, and presence of hypertension. The mean estimated glomerular filtration rate (eGFR) values of FG and NFG were 86.4 +/- 18.5 and 66.1 +/- 36.5 mL/min/1.73m(2), respectively. During the follow-up period. no significant changes occurred in BR weight, creatinine, 24-hour urine volume. NGAL, KIM-1, or GFR in either group (p > 0.05), while 24-hour urinaly protein was significantly decreased in FG (p < 0.001). Conclusion:. A fasting duration of similar to 17 hours a day did not affect renal function negatively in patients with early-stage chronic kidney disease due to ADPKD. Also, no significant changes occurred in acute renal failure markers.
dc.subjectHealth Sciences
dc.subjectDahili Tıp Bilimleri
dc.subjectİç Hastalıkları
dc.subjectSağlık Bilimleri
dc.subjectKlinik Tıp (MED)
dc.subjectKlinik Tıp
dc.titleEffects of fasting during the month of Ramadan on renal function in patients with autosomal dominant polycystic kidney disease
dc.relation.journalCLINICAL NEPHROLOGY
dc.contributor.departmentBezmiâlem Vakıf Üniversitesi , ,

Files in this item


There are no files associated with this item.

This item appears in the following Collection(s)

Show simple item record