Unilateral Ablative Lesions of the Subthalamic Nucleus in Moderate-to-Advanced Parkinson's Disease

Abstract

Objective: Deep brain stimulation (DBS) of the subthalamic nucleus (STN) has been reported to be effective in alleviating all parkinsonian motor symptoms and motor complications in moderate-to-advanced Parkinson's disease (PD). We have studied the effects of unilateral STN lesions on moderate-to-advanced PD.