Intercellular Adhesion Molecule-1 Lys469Glu Polymorphism, Systemic Redox Homeostasis and Gestational Diabetes Mellitus in Pregnant Women

Tarih
2019
Yazar
Turan, Saime
Kucukhuseyin, Özlem
Simsek, Bahadir
Yanar, Karolin
Yaylim, Ilhan
Sitar, Mustafa Erinc
Aydin, Seval
Tuten, Abdullah
Benian, Ali
Cakatay, Ufuk
Cacina, Canan
Üst veri
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Özet
Objectives: Intercellular adhesion molecule-1 (ICAM-1) plays an important role in endothelial function. Hyperglycemia-induced impaired redox status is 1 of the well-known pathophysiologic characteristics of gestational diabetes mellitus (GDM), and it plays a crucial role in the causes of disease. Our aim was to clarify any possible relationship between the ICAM-1 Lys469Glu polymorphism and systemic redox status in women with and without GDM. Also, we investigated whether this polymorphism could be associated with a change for better or worse as evidenced by clinical and redox biomarkers.
Bağlantı
http://hdl.handle.net/20.500.12627/15924
https://doi.org/10.1016/j.jcjd.2018.07.003
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