Are IVS4 SNPs of OLR1 gene associated with coronary artery disease: Is there a linkage between IVS4 SNPs?

Yazar
Yilmaz-Aydogan, Hulya
Kucukhuseyin, Ozlem
Ozkok, Elif
Bugra, Zehra
Ozturk, Oguz
Kurnaz-Gomleksiz, Ozlem
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Özet
Background. The OLR1 gene has been identified as a candidate gene for coronary artery disease (CAD). Six single-nucleotide polymorphisms (SNPs) of the OLR1 gene located within intron 4 (IVS4-27G>C, IVS4-73C>T, IVS4-14A>G), intron 5 (IVS5-70A>G, IVS5-27G>T) and 3'UTR (188C>T) comprise a linkage disequilibrium (LD) block, which is strongly associated with the elevated risk of CAD.
Bağlantı
http://hdl.handle.net/20.500.12627/152390
https://doi.org/10.17219/acem/68395
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