Indirect assessment of the maximum empirical activity (250 mCi) with respect to dosimetry concepts in radioiodine therapy of metastatic differentiated thyroid cancer

Abstract

Aim The development of reliable dosimetry models promotes the individualized therapy concept toward more success and less complications. This paper evaluates the traditional maximum empirical activity (250 mCi) and the benefit of joining two dosimetry approaches to optimize the therapeutic activity and radioiodine efficacy in metastatic differentiated thyroid cancer.