Tissue sialic acid and fibronectin levels in human prostatic cancer

Abstract

We investigated the tissue concentration of sialic acid and fibronectin in patients with prostatic cancer. The mean sialic acid and fibronectin levels in patients with prostatic cancer were 19.02 +/- 6.30 mu g/mg protein and 20.22 +/- 7.13 mu g/mg protein, respectively versus 13.01 +/- 4.53 mu g/mg protein and 11.77 +/- 6.74 mu g/mg protein for normal prostatic tissues. Sialic acid and fibronectin levels in cancerous patients were significantly higher than in the control group (P < 0.05).