Serum and Urinary Levels of Tumor Necrosis Factor-Alpha in Renal Transplant Patients

Abstract

Objectives: Allograft rejection is an important cause of early and long-term graft loss in kidney transplant recipients.Tumor necrosis factor-alpha promotes T-cell activation, the key reaction leading to allograft rejection. Here, we investigated whether serum and urinary tumor necrosis factor-alpha levels can predict allograft rejection.