Cytokine gene variants/expressions and non-syndromic microtia - is there a link?

Abstract

Objective: Although many genetic and environmental factors are investigated the etiopathogenesis of microtia, it still remains unclear. We investigated the relationship between the variants/expression of pro-and anti-inflammatory cytokines [interleukin (IL) 6, IL-10, tumor necrosis factor-alpha (TNF-alpha), transforming growth factor beta (TGF-beta 1), interferon gamma (IFN-gamma)] and susceptibility non-syndromic microtia in a Turkish cohort.