Molecular Characterization of Drug Resistance in Hepatitis B Viruses Isolated from Patients with Chronical Infection in Turkey

Tarih
2018
Yazar
TURGUT, HÜSEYİN
Tulek, Necla Eren
DEMİR, NAZLIM AKTUĞ
Mistik, Resit
Ormen, Bahar
Korkmaz, Fatime
Yildirmak, Taner
URAL, ONUR
Aydin, Mehtap
Asan, Ali
SAYAN, MURAT
Eraksoy, Haluk
DEMİRTÜRK, NEŞE
Gunal, Ozgur
AKHAN, SILA
Koruk, Suda Tekin
AYGEN, BİLGEHAN
SIRMATEL, FATMA
Tuna, Nazan
Kose, Sukran
Kaya, Ali
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Özet
Background: Hepatitis B virus (HBV) has a high mutation rate due to its unusual replication strategy leading to the production of a large number of virions with single and double mutations. The mutations, in turn, are associated with the development of drug resistance to nucleos(t)ide analogs (NUCs) in patients before and during NUCs therapy.
Bağlantı
http://hdl.handle.net/20.500.12627/147367
https://doi.org/10.5812/hepatmon.12472
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