Evaluation of material heterogeneity dosimetric effects using radiochromic film for COMS eye plaques loaded with I-125 seeds (model I25.S16)

Abstract

Purpose: (1) To measure absolute dose distributions in eye phantom for COMS eye plaques with I-125 seeds (model I25.S16) using radiochromic EBT film dosimetry. (2) To determine the dose correction function for calculations involving the TG-43 formalism to account for the presence of the COMS eye plaque using Monte Carlo (MC) method specific to this seed model. (3) To test the heterogeneous dose calculation accuracy of the new version of Plaque Simulator (v5.3.9) against the EBT film data for this seed model.