EFFECTS OF ALL-TRANS RETINOIC ACID ON REDUCING HYPEROXIA-INDUCED OXIDATIVE STRESS IN MICE BRAIN

Abstract

Objective: Brain is a very sensitive organ to oxidative stress due to its large amount of polyunsaturated fatty acid content and low antioxidant activity In this study, effect of exogenous all-trans-retinoic acid (RA) on brain antioxidant activity was investigated in mice under hyperoxia-induced oxidative stress.