Effects of probiotics on some acute phase proteins in broilers exposed to Salmonella typhimurium lipopolysaccharides

Abstract

In this study the effects of two commercial probiotic preparations - Broilact used via drinking water and Bioplus 2B used via diet - on immunological response of the broilers that were sensitized with IP S. typhimurium LPS (lipopolyisaccharide) application were investigated. The effects were verified by determination of changes in some acute phase proteins including albumin, fibrinogen, ceruloplasmin, total protein and trasferrin. The study was conducted on 300 "Ross 308" broilers. Three ml of S. typhimurium LPS was applied to each broiler in trial group intraperitoneal on day 20 of the study. S. typhimurium LPS was not applied to control group broilers. The experimental design included 2 groups, control (no LPS exposure) and trial group (LPS exposure). Each group was divided into 3 subgroups as Check, Bro and Bio and each of the subgroup contained 50 broilers. These subgroups were arranged as below: