Liposarcoma: Atypical Spread with Intraperitoneal and Vertebral Metastasis in a Young Female

Abstract

Myxoid and round cell liposarcoma commonly occur in the thigh and retroperitoneum, and an intraperitoneal location and bony spread are rare. A young woman was admitted with the complaint of right thigh pain. Tru-cut biopsy revealed well-differentiated myxoid and round cell liposarcoma. Following chemoradiotherapy, the mass was removed with wide local excision. A vertebral metastasis at the 11th thoracic vertebra was discovered 11 months later. Following chemoradiotherapy, the corpus of the 11th thoracic vertebra was excised, and an implant was placed. Six months later, abdominopelvic magnetic resonance imaging (MRI) demonstrated a giant pelvic mass. Hysterectomy, lower anterior resection of the sigmoid colon, and removal of 8 cm of jejunum were performed. After 4 months, masses in the left abdominal wall, left axilla, and nearby pancreas were detected. Pathology was low-grade myxoid liposarcoma. This uncommon pattern of spread should certainly be taken into account when determining prognosis.