Re-exploring Planaria as a model organism for genotoxicity monitoring by an "improved random amplified polymorphic DNA (RAPD)*" approach

Abstract

In monitoring genotoxicity, it is important to have sensitive, but non-specific assays to indicate a wide range of DNA damage mechanisms. In this paper, a new and flexible approach for the qualitative detection of induced DNA effects, DNA damages and mutations, accelerated by exploiting planaria regeneration and using an improved RAPD assay, is presented.