Determination of clinical significance of coagulase-negative staphylococci in blood cultures
Tarih
2017Yazar
Midilli, Kenan
Kuskucu, Mert Ahmet
Kucukbasmaci, Omer
Aygun, Gokhan
Ergin, Sevgi
Karakullukcu, Asiye
Üst veri
Tüm öğe kaydını gösterÖzet
The aim of this study was to investigate the criteria used to distinguish coagulase-negative staphylococci (CoNS) bacteremia from contamination. We evaluated 162 adult patients with CoNS-positive blood cultures (BCs). Of the 162 patients, 35 (21.6%) had at least 2 positive BCs and 127 (78.4%) had a single positive BC. According to the Laboratory-Confirmed Bloodstream Infection (LCBI) criteria, 24 (14.8%) patients with the same species of CoNS had true bacteremia, and 138 (85.2%) patients had contaminants. Despite the detection of the same CoNS species, 9 of the 24 patients had different CoNS genotypes. Using clinical assessments, only 20 patients were diagnosed with true bacteremia, 8 of them had a single positive BC. We concluded that only using the LCBI criteria or clinical evaluations of a patient were not sufficient to distinguish CoNS bacteremia from contamination. Molecular identification should also be performed as a diagnostic laboratory parameter for CoNS bacteremia. (C) 2016 Elsevier Inc. All rights reserved.
Bağlantı
http://hdl.handle.net/20.500.12627/119241https://doi.org/10.1016/j.diagmicrobio.2016.12.006
Koleksiyonlar
- Makale [92796]