Radio labelling of peptides for PET, SPECT and therapeutic applications using a fully automated disposable cassette system

Tarih
2011
Yazar
Haubner, Roland
Ocak, Meltem
von Guggenberg, Elisabeth
Silbernagl, Roland
Decristoforo, Clemens
Petrik, Milos
Knetsch, Peter A.
Knopp, Roger
Imperato, Giovanni
Üst veri
Tüm öğe kaydını göster
Özet
Objectives Radio labelled somatostatin analogues have found wide clinical use in nuclear medicine for both diagnostic and therapeutic applications. Here, we describe the development of a fully automated synthesis system allowing radiolabelling of 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid (DOTA)-derivatized peptides with (68)Ga/(111)In/(177)Lu and (90)Y, meeting radiation safety and. pharmaceutical requirements.
Bağlantı
http://hdl.handle.net/20.500.12627/11668
https://doi.org/10.1097/mnm.0b013e3283497188
Koleksiyonlar