The Effect of ZAP-70 Expression on Disease Progression in Early-Stage (Binet A) B-CLL Patients

Date
2009
Author
Ar, Muhlis Cem
ULKU, Birsen
Baslar, Zafer
Ongoren, Seniz
Gulseven, Muhterem
Tuzuner, Nuekhet
FERHANOGLU, Burhan
URE, Uemit
Aydin, Yıldız
Soysal, Teoman
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Abstract
Objectives: Chronic lymphocytic leukemia (CLL) is a heterogeneous disease with various clinical findings. Prognostic markers predicting the clinical outcome in early-stage CLL would play a major role in disease management. Various studies have shown that zeta-associated protein 70 (ZAP-70) provides significant prognostic information This retrospective, single-centre study evaluates the effect of ZAP-70 on disease progression in early-stage B-CLL
URI
http://hdl.handle.net/20.500.12627/11291
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