The effect of heme oxygenase-1 induction by glutamine on TNBS-induced colitis - The effect of glutamine on TNBS colitis

Abstract

Background Inflammatory bowel disease is a multifactorial inflammatory disease of the colon and rectum with an unknown etiology. In the present study, we aimed to investigate whether heme oxygenase-1 (HO-1) induction by glutamine could protect colitis-induced damage from oxidative, inflammatory, and apoptotic damage.