Two siblings with hiomocystinuria presenting with dystonia and parkinsonism

Abstract

Movement disorders such as dystonia, chorea or tremor are rarely encountered in patients with homocystinuria. We present 2 siblings with laboratory-confirmed homocystinuria, one with severe generalized dystonia and the other with mild parkinsonism. The movement disorders in our patients appeared in the second and first decades, respectively. (C) 2004 Movement Disorder Society.