Selective nuclear factor kappa-B inhibitors, pyrolidium dithiocarbamate and sulfasalazine, prevent the nephrotoxicity induced by gentamicin

Date
2006
Author
Somay, Adnan
Altug, Tuncay
Ozdogan, Haci K.
Cekmen, Mustafa B.
Karaca, Cetin
Tugcu, Volkan
Tasci, Ali I.
Kemahli, Eray
Bas, Muzaffer
Ozbek, Emin
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Abstract
OBJECTIVE To investigate the effect of selective nuclear factor kappa-B (NF kappa-B) inhibitors, pyrolidium dithiocarbamate (PD) and sulfasalazine (SZ) on renal tubular necrosis and inducible nitric oxide synthase (iNOS) and NF kappa-B expression induced by gentamicin in rats.
URI
http://hdl.handle.net/20.500.12627/103321
https://doi.org/10.1111/j.1464-410x.2006.06321.x
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