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Potentiation of cytotoxicity by combination of imatinib and chlorimipramine in glioma.
Rat C6 glioma is a chemo-resistant experimental brain tumor that is difficult to treat with various drug combinations. Previous studies suggested that imatinib mesylate (Gleevec) is effective in pre-clinical trials for ...
SET oncogene is upregulated in pediatric acute lymphoblastic leukemia
Aims and background. The SET gene is a target of chromosomal translocations in acute leukemia and encodes a widely expressed multifunctional phosphoprotein. It has been shown that SET is upregulated in BCR-ABL1-positive ...